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Wed · May 7, 2026 · 06:42 ETFDA’s PCAC delays Cat 2 review on tirzepatide compounds; vendors quietly recalibrating.
Editor’s full note →
The pulse · Issue №347

The peptide market, read carefully.

Studies, regulatory shifts, vendor scoring, community signal. Updated daily by editors who actually read the methods sections.

1,847
studies indexed
312
peptides tracked
47
vendors scored
14,231
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The Sunday Brief

One email Sunday morning. The week in peptides, signal-only.

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Updated 3h ago

Newest studies

NEW
BPC-157 attenuates colitis-induced inflammation in a murine model
Mixed
J. Gastroenterol Res.n=48 MouseMay 6
Retatrutide 12mg weekly: 24-week glycemic and weight outcomes
Supported
NEJMn=312 HumanMay 5
GHK-Cu topical efficacy on photoaged skin: a sham-controlled RCT
Weak / none
JAADn=96 HumanMay 4
All studies →
Updated 11h ago

Regulatory watch

FDAMay 6
PCAC defers Cat 2 vote on tirzepatide compounds to July session
Compounders extended status quo through Q3. Industry letter notes shortage list still active.
USPMay 4
Draft monograph for sermorelin published for public comment
Comment window 60 days. Defines impurity thresholds at 0.5%.
DEAMay 3
Methylene blue scheduling rumor — what's actually true
Editor: there is no proposed rule. The viral post misread a 2023 letter.
Updated 26m ago

From the community

NEW
r/Peptides · 312 comments · 11hpositive
Two months on retatrutide — sharing my labs
OP reports 11.4% bodyweight loss, no adverse hepatic markers. Comments flag missing baseline.
r/PeptideHarm · 148 comments · 1dmixed
Reconstitution sterility — what people get wrong
Discussion converges on bac-water vs. sterile-water debate. Cited mostly hearsay.
r/Nootropics · 74 comments · 2dmixed
Selank for anxiety — dose-response thread
50+ replies. Anecdotal, no labs. Editor: trial-quality evidence remains limited.
Search trends, 7d

Trending peptides

Retatrutide
+148%
Tirzepatide
+24%
BPC-157
−6%
Methylene Blue
+312%
Cagrilintide
+11%
TB-500
−18%
Featured

The investigation

[ INVESTIGATION HERO ]
INVESTIGATION · 18 min read

Inside the gray-market reconstitution-water shortage that nobody is talking about

Six manufacturers, three FDA inspections, and the supply-chain bottleneck quietly raising contamination risk for tens of thousands of users.

By Sarah Chen · May 4
[ PRIMER HERO ]
PRIMER · 22 min read

Reading a peptide trial like an editor: a working primer

What N=12 actually means, why species matters more than dose, and the four phrases in an abstract that should make you keep scrolling.

By Dr. M. Olawale · May 1
Updated weekly

Top vendors

1
Limitless Life
SAB-3 letter posted
COA + service
A−
2
Peptide Sciences
Stable
COA + research-only
A
3
Pure Rawz
New COA partner
Fast ship · COA gaps
B+
4
Modern Aminos
Out of stock 4 SKUs
Inconsistent COA
B
5
Amino Asylum
Quietly raised pricing
Service problems
C
312 indexed

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